A fetus with a parvovirus B19 infection and congenital anomalies

Prenat Diagn. 1994 Mar;14(3):173-6. doi: 10.1002/pd.1970140305.

Abstract

A fetus with multiple structural defects was seen at prenatal ultrasound examination. After termination of the pregnancy a bilateral cleft lip, alveolus, and palate; micrognathia; and webbed joints were seen. Fetal tissues showed indications of infection, intranuclear inclusion bodies, chronic stress, haemolysis, arterial wall damage, and profuse haemorrhage. Parvovirus B19 DNA was detected in fetal tissues by dot hybridization after polymerase chain reaction. The possibility of parvovirus B19 infection leading to congenital malformations is discussed.

Publication types

  • Case Reports
  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Congenital Abnormalities / diagnostic imaging*
  • Congenital Abnormalities / microbiology
  • Female
  • Fetal Diseases / diagnostic imaging*
  • Fetal Diseases / microbiology
  • Humans
  • Parvoviridae Infections / diagnostic imaging*
  • Parvovirus B19, Human*
  • Pregnancy
  • Ultrasonography