Development of invasive adenocarcinoma following colectomy with ileoanal anastomosis for familial polyposis coli. Report of a case

Dis Colon Rectum. 1994 Aug;37(8):824-8. doi: 10.1007/BF02050149.


Purpose: Proctocolectomy with ileoanal anastomosis has gained increasing acceptance for the prophylactic treatment of patients with familial polyposis coli. Long-term surveillance of the ileal pouch and the pouch-anal anastomosis has not been emphasized despite concern regarding retained rectal mucosa following the procedure.

Methods: A 34-year-old patient with a strong family history of familial polyposis coli was treated at 14 years of age by single-stage proctocolectomy with straight ileoanal anastomosis. Follow-up proctoscopic examinations revealed development of adenomatous changes at the ileoanal anastomosis.

Results: This report presents a patient with familial polyposis coli who developed invasive adenocarcinoma at the ileoanal anastomosis 20 years after proctocolectomy with ileoanal anastomosis.

Conclusions: We stress the need for lifelong proctoscopic surveillance in patients with familial polyposis coli treated by proctocolectomy with ileoanal anastomosis.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / epidemiology
  • Adenocarcinoma / pathology*
  • Adenocarcinoma / surgery
  • Adenomatous Polyposis Coli / surgery*
  • Adult
  • Female
  • Follow-Up Studies
  • Humans
  • Ileal Neoplasms / epidemiology
  • Ileal Neoplasms / pathology*
  • Ileal Neoplasms / surgery
  • Ileum / pathology
  • Neoplasms, Second Primary / epidemiology
  • Neoplasms, Second Primary / pathology*
  • Neoplasms, Second Primary / surgery
  • Proctocolectomy, Restorative*
  • Time Factors