The efficacy of two new tiny snares has been evaluated for removal of diminutive (7 mm or less) colorectal polyps. The small size of the snares facilitates direct placement over a polyp, after which resection can be performed using monopolar current. Data were prospectively collected on 183 polyps, 2 to 7 mm in diameter, encountered in 90 patients. Polyp diameter, location relative to the splenic flexure, and histologic characteristics were noted, as were retrieval rate and complications. Ninety-four percent of the polyps could be removed with a tiny snare, and 88% of these were recovered. Forty percent of the polyps were located proximal to the splenic flexure, and 69% were neoplastic. The only complication was major hemorrhage in 1 patient (0.5%), in whom snare polypectomy without current application was used. Tiny snares can effectively and safely be used to remove diminutive colorectal polyps, and they may make "hot biopsy" forceps obsolete.