Disseminated cutaneous and meningeal sporotrichosis in an AIDS patient

Diagn Microbiol Infect Dis. 1994 Feb;18(2):111-5. doi: 10.1016/0732-8893(94)90075-2.


We report the first proven case of Sporothrix meningoencephalitis in an AIDS patient. The patient had dramatic, wide-spread ulcerative and infiltrative disease with progressive meningoencephalitis in spite of amphotericin and itraconazole therapy. Sporothrix was cultured from premortem cerebrospinal fluid and seen in the meninges and in brain vessels at autopsy.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / pathology*
  • Adult
  • Fluconazole / therapeutic use
  • Humans
  • Male
  • Meningoencephalitis / complications*
  • Meningoencephalitis / drug therapy
  • Meningoencephalitis / pathology
  • Sporothrix
  • Sporotrichosis / complications*
  • Sporotrichosis / drug therapy
  • Sporotrichosis / pathology


  • Fluconazole