LRG1 is expressed during sporulation in Saccharomyces cerevisiae and contains motifs similar to LIM and rho/racGAP domains

Nucleic Acids Res. 1994 Aug 11;22(15):3151-4. doi: 10.1093/nar/22.15.3151.

Abstract

We here report the sequence of a yeast gene LRG1 whose deduced amino acid sequence contains sequence motifs similar to LIM domain proteins in the amino-terminal, and to rho/rac GTPase activating proteins (rho/racGAP's) in the carboxy-terminal part. LRG1 expression is differentially regulated showing a peak of expression in sporulating cells. Gene disruption experiments indicate that the gene is not essential and may play a role during mating.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • DNA, Fungal / chemistry
  • DNA, Fungal / isolation & purification
  • DNA-Binding Proteins / chemistry*
  • DNA-Binding Proteins / genetics*
  • GTP-Binding Proteins / chemistry*
  • GTPase-Activating Proteins
  • Gene Expression*
  • Genes, Fungal*
  • Molecular Sequence Data
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae / physiology
  • Saccharomyces cerevisiae Proteins*
  • Sequence Homology
  • Spores, Fungal / physiology*
  • rac GTP-Binding Proteins

Substances

  • DNA, Fungal
  • DNA-Binding Proteins
  • GTPase-Activating Proteins
  • LRG1 protein, S cerevisiae
  • Saccharomyces cerevisiae Proteins
  • GTP-Binding Proteins
  • rac GTP-Binding Proteins

Associated data

  • GENBANK/X78453