Malignant hyperpyrexia in oral surgery--case report and literature review

Br J Oral Maxillofac Surg. 1994 Jun;32(3):190-3. doi: 10.1016/0266-4356(94)90109-0.


A case of malignant hyperpyrexia (MH) occurring in a patient undergoing orthognathic surgery is reported which resulted in the procedure being abandoned prior to completion. The oral surgeon's role in recognising the early clinical signs of masseteric spasm and central cyanosis is highlighted. The case shows that with proper investigation and management the MH susceptible patient was able to have a second anaesthetic with safety to complete the surgery.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Anesthesia, Dental / adverse effects*
  • Anesthesia, Inhalation / adverse effects*
  • Cyanosis / etiology
  • Female
  • Humans
  • Intraoperative Complications*
  • Malignant Hyperthermia* / etiology
  • Malocclusion / surgery
  • Masseter Muscle / physiopathology
  • Orthognathic Surgical Procedures
  • Osteotomy / adverse effects
  • Succinylcholine / adverse effects*
  • Trismus / etiology


  • Succinylcholine