Pattern of drug usage in bronchiolitis

J Clin Pharm Ther. 1994 Apr;19(2):117-8. doi: 10.1111/j.1365-2710.1994.tb01122.x.

Abstract

Bronchiolitis is a common viral respiratory infection in infants and young children. The objective of this study was to assess the pattern of drug usage in paediatric patients with bronchiolitis. One hundred patients (aged 2 weeks to 22 months) were evaluated. Of these, 64% had a respiratory syncytial virus infection. The drug therapy included albuterol in 99%, corticosteroids in 36%, aminophylline in 12% and ribavirin in 2% of the patients. The drug doses and frequencies, and durations of therapy varied substantially among patients. This emphasizes the need for well-designed research to develop optimal dosage regimens in paediatric patients with bronchiolitis.

MeSH terms

  • Albuterol / administration & dosage
  • Albuterol / therapeutic use
  • Aminophylline / administration & dosage
  • Aminophylline / therapeutic use
  • Bronchiolitis, Viral / drug therapy*
  • Bronchiolitis, Viral / microbiology
  • Drug Utilization / trends
  • Female
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / therapeutic use
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Respiratory Syncytial Virus Infections / drug therapy
  • Ribavirin / administration & dosage
  • Ribavirin / therapeutic use

Substances

  • Glucocorticoids
  • Aminophylline
  • Ribavirin
  • Albuterol