A mitochondrial group-I intron in fission yeast encodes a maturase and is mobile in crosses

B Schäfer; B Wilde; D R Massardo; F Manna; L Del Giudice; K Wolf

doi:10.1007/BF00351487

A mitochondrial group-I intron in fission yeast encodes a maturase and is mobile in crosses

Curr Genet. 1994 Apr;25(4):336-41. doi: 10.1007/BF00351487.

Authors

B Schäfer¹, B Wilde, D R Massardo, F Manna, L Del Giudice, K Wolf

Affiliation

¹ Institut für Biologie IV (Mikrobiologie), Rheinisch-Westfälische Technische Hochschule, Aachen, Germany.

PMID: 8082176
DOI: 10.1007/BF00351487

Abstract

The open reading frame in the first intron of the mitochondrial gene encoding subunit I of cytochrome c oxidase encodes a maturase and stimulates homologous recombination in Escherichia coli. In this paper, we demonstrate that this intron is mobile in crosses, indicating that it also encodes an endonuclease. This is the first report on an intron which possesses mobility and acts as a maturase.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Cloning, Molecular
Crosses, Genetic*
DNA Transposable Elements / genetics
DNA, Mitochondrial / genetics*
Drug Resistance, Microbial / genetics
Endonucleases / genetics
Endoribonucleases / genetics*
Genetic Code
Introns*
Nucleotidyltransferases / genetics*
Saccharomyces cerevisiae / genetics
Schizosaccharomyces / genetics*

Substances

DNA Transposable Elements
DNA, Mitochondrial
Nucleotidyltransferases
mRNA maturase
Endonucleases
Endoribonucleases