Do "screening" coagulation tests predict bleeding in patients undergoing fiberoptic bronchoscopy with biopsy?

Chest. 1994 Sep;106(3):703-5. doi: 10.1378/chest.106.3.703.


Objective: To determine if preprocedure coagulation testing predicts bleeding in patients undergoing flexible fiberoptic bronchoscopy (FOB) with biopsy.

Design: Retrospective chart review.

Setting: Southeastern, urban Veteran Affairs Medical Center.

Measurements and main results: Two hundred seventy-four patient charts representing 305 FOB with biopsy were reviewed for clinical predictors of bleeding, prebronchoscopy laboratory abnormalities, and incidence of bleeding complications. Thirty-five patients bled, and 3 had abnormal results of coagulation studies. Normal results of coagulation studies and no clinical risk factors were noted in 68 percent of patients who bled.

Conclusion: Patients undergoing flexible FOB with biopsy do not benefit from preprocedure coagulation testing.

MeSH terms

  • Biopsy / adverse effects
  • Biopsy / statistics & numerical data
  • Blood Coagulation Tests*
  • Bronchi / pathology*
  • Bronchial Diseases / epidemiology
  • Bronchial Diseases / etiology*
  • Bronchoscopy / adverse effects*
  • Bronchoscopy / statistics & numerical data
  • Chi-Square Distribution
  • Fiber Optic Technology
  • Hemorrhage / epidemiology
  • Hemorrhage / etiology*
  • Humans
  • Partial Thromboplastin Time
  • Preoperative Care / statistics & numerical data
  • Prevalence
  • Prognosis
  • Prothrombin Time
  • Retrospective Studies
  • Risk Factors
  • Virginia / epidemiology