Protocol management of adult respiratory distress syndrome

New Horiz. 1993 Nov;1(4):593-602.


Protocol control of severely ill ICU patients seems feasible. A satisfactory computer infrastructure makes protocol control practical. A reported four-fold survival rate increase associated with protocol control of ventilatory management of adult respiratory distress syndrome patients suggests that it is not harmful. Protocol control represents a medical decision-support approach for standardizing therapy. Computerized protocols might provide a solution to the nonuniformity of care in clinical ICU practice and investigation. My colleagues and I can envision a multicenter consortium of hospitals equipped to carry out computerized protocol-controlled care. Such a consortium could rapidly complete large, randomized, clinical trials under computerized protocol control. This arrangement could provide much more definitive results than are currently possible. Interpretation of outcomes research results should thereby be made easier and conclusions should be more credible and more likely to contribute to medical policy formulation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adult
  • Blood Gas Analysis
  • Clinical Protocols
  • Critical Care / methods
  • Data Interpretation, Statistical
  • Decision Making, Computer-Assisted
  • Decision Support Techniques
  • Feasibility Studies
  • Humans
  • Multicenter Studies as Topic
  • Positive-Pressure Respiration / adverse effects
  • Positive-Pressure Respiration / methods*
  • Randomized Controlled Trials as Topic
  • Respiratory Distress Syndrome / blood
  • Respiratory Distress Syndrome / mortality
  • Respiratory Distress Syndrome / therapy*
  • Severity of Illness Index
  • Survival Rate
  • Treatment Outcome