Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII

Science. 1994 Sep 30;265(5181):2077-82. doi: 10.1126/science.8091229.


The complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII reveals that it contains 269 predicted or known genes (300 base pairs or larger). Fifty-nine of these genes (22 percent) were previously identified. Of the 210 novel genes, 65 are predicted to encode proteins that are similar to other proteins of known or predicted function. Sixteen genes appear to be relatively recently duplicated. On average, there is one gene approximately every 2 kilobases. Although the coding density and base composition across the chromosome are not uniform, no regular pattern of variation is apparent.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Base Composition
  • Base Sequence
  • Chromosome Mapping
  • Chromosomes, Fungal*
  • DNA, Fungal / genetics
  • Genes, Fungal*
  • Introns
  • Multigene Family
  • Open Reading Frames
  • RNA, Fungal / genetics
  • RNA, Transfer / genetics
  • Saccharomyces cerevisiae / genetics*


  • DNA, Fungal
  • RNA, Fungal
  • RNA, Transfer