The knowledge of the skin surface pH-acid mantle is updated. The conviction that chronic alkalinization is damaging has been strengthened. Extensive skin surface pH data on the skin of non-white people are still missing. In the case of any measurement, the need for extensive infrastructural research and evaluation by non-parametric methods is emphasized. Infrastructural studies evaluate the range and change of the measured parameters for each test method according to sex, age and body area, as well as the sensitivity of the method to pharmacological influences. A detailed knowledge of the normal-representative range would make it possible to select those individuals whose measured parameter is outside the main 95% of the population; a detailed study of such individuals would be a very effective method of understanding the basic regulatory mechanism of the measured parameter.