[Necrotizing sarcoid granulomatosis. Apropos of 4 cases]

Ann Med Interne (Paris). 1994;145(4):230-3.
[Article in French]


Necrotizing sarcoid granulomatosis (NSG) was first described by Liebow in 1973 among the heading "pulmonary angeitis and granulomatosis". We reported four cases of NSG. The diagnostic was made by open lung biopsy in all, and the distinctive features were those described by Liebow: presence of numerous sarcoid-like granulomas, foci of fibrinoid necrosis and granulomatous vasculitis. Clinical, radiological, and clinical course characteristics allow the reasonable conclusion that NSG is the histopathological substratum of a variety of sarcoidosis affections termed "nodular sarcoidosis".

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adult
  • Female
  • Granuloma / pathology*
  • Humans
  • Male
  • Necrosis
  • Sarcoidosis, Pulmonary / pathology*
  • Time Factors