Total cholesterol, high density lipoprotein cholesterol and steroid hormone changes in normal weight women during the menstrual cycle

Int J Gynaecol Obstet. 1993 Jun;41(3):265-8. doi: 10.1016/0020-7292(93)90554-a.

Abstract

Objective: To study total cholesterol, high density lipoprotein cholesterol and steroid changes in normal weight women during the menstrual cycle.

Method: Multiple point blood samples obtained at different phases of the menstrual cycle in 14 student nurses, consuming normal Nigerian diets (rich in vegetable based proteins and fiber), were analyzed for HDL cholesterol, total cholesterol and for the steroids progesterone, estradiol and testosterone by RIA.

Results: A multivariate repeated measures analysis was carried out according to Pillais, Hotelings Willes and Roys tests and the three phases of menstrual cycle were found to be significantly different with the significance level at 0.030.

Conclusion: The fluctuations in plasma lipids that occur at different phases of the menstrual cycle have important implications in evaluating the factors of coronary heart disease in women of reproductive age. Also, the results suggest that multiple point measurements may give a better estimate of plasma lipid changes in blood in women of reproductive age.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Body Weight
  • Cholesterol / blood*
  • Cholesterol, HDL / blood
  • Estradiol / blood*
  • Female
  • Follicular Phase
  • Humans
  • Luteal Phase
  • Menstrual Cycle / physiology*
  • Multivariate Analysis
  • Progesterone / blood*
  • Reference Values

Substances

  • Cholesterol, HDL
  • Progesterone
  • Estradiol
  • Cholesterol