Acute exogenic psychosis following oral ingestion of 2 mg lormetazepam in an eleven-year-old boy

Pharmacopsychiatry. 1993 May;26(3):102-3. doi: 10.1055/s-2007-1014352.

Abstract

After oral ingestion of 2 mg lormetazepam given by his mother, an 11-year-old boy suffered from severe adverse effects. Main symptoms were disorientation, restlessness, amnesia, anxiety, hostility, and rage reactions. Paranoid ideations and impaired perception were concluded from strange reactions and remarks of the child. Symptoms are similar to the van der Kroef syndrome described after the use of rapidly eliminated high-potency benzodiazepines. This case demonstrates drug abuse on the part of parents wishing to induce sleep in their children.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Animals
  • Anti-Anxiety Agents / poisoning*
  • Benzodiazepines*
  • Child
  • Electroencephalography
  • Guinea Pigs
  • Humans
  • Lorazepam / analogs & derivatives*
  • Lorazepam / poisoning
  • Male
  • Psychoses, Substance-Induced / psychology*

Substances

  • Anti-Anxiety Agents
  • Benzodiazepines
  • lormetazepam
  • Lorazepam