Centrilobular opacities in the lung on high-resolution CT: diagnostic considerations and pathologic correlation

AJR Am J Roentgenol. 1994 Mar;162(3):569-74. doi: 10.2214/ajr.162.3.8109498.


Accurate assessment of high-resolution CT scans of the lung requires a knowledge of secondary lobular anatomy. Opacity that localizes to the centrilobular region implies the presence of a disease process that primarily involves centrilobular bronchioles, lymphatics, or pulmonary arterial branches. We illustrate the high-resolution CT findings of many of these processes and provide pathologic correlation for cases in which it was available.

MeSH terms

  • Humans
  • Lung / anatomy & histology
  • Lung / diagnostic imaging*
  • Lung / pathology
  • Lung Diseases / diagnostic imaging
  • Lung Diseases / pathology
  • Radiographic Image Enhancement
  • Tomography, X-Ray Computed*