Characterization of a weak allele of the GL1 gene of Arabidopsis thaliana

Plant Mol Biol. 1994 Jan;24(1):203-7. doi: 10.1007/BF00040586.


A genomic clone containing the gl1-2 allele has been isolated and sequenced. The predicted amino acid sequence of the gl1-2 protein is identical to that of the GL1-Col allele up to position 201. At this point in the coding region of gl1-2 there is a deletion relative to the wild-type sequence that results in an in-frame stop codon at position 202. This deletion removes 27 amino acid residues, including a highly negatively charged region, from the predicted gl1-2 polypeptide. The loss of this negatively charged carboxy-terminal region from the gl1-2 product is most likely the cause of the partial loss of gene activity which results in a reduction in leaf trichome initiation.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Alleles
  • Amino Acid Sequence
  • Arabidopsis / genetics*
  • Arabidopsis / ultrastructure
  • Arabidopsis Proteins*
  • Base Sequence
  • Cloning, Molecular
  • DNA
  • DNA-Binding Proteins*
  • Exons
  • Genes, Plant*
  • Molecular Sequence Data
  • Plant Proteins / genetics*
  • Sequence Homology, Amino Acid
  • Sequence Homology, Nucleic Acid


  • Arabidopsis Proteins
  • DNA-Binding Proteins
  • Plant Proteins
  • GL1 protein, Arabidopsis
  • DNA

Associated data

  • GENBANK/L22786