Evidence for cell surface control of macronuclear DNA synthesis in Stentor

Nature. 1975 Nov 27;258(5533):300-3. doi: 10.1038/258300a0.


In cell grafts, Stentor macronuclei associated with separate regions of cell surface can be made asynchronous with regard to morphology and DNA synthesis even though they demonstrably share a common endoplasm. These results suggest a mechanism for nuclear differentiation within a single cytoplasmic compartment, based on cell surface differences.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Cell Differentiation
  • Cell Nucleus / metabolism
  • Ciliophora / cytology
  • Ciliophora / metabolism*
  • Ciliophora / ultrastructure
  • Cytoplasm / metabolism
  • DNA / biosynthesis*
  • Regeneration
  • Surface Properties
  • Thymidine / metabolism
  • Time Factors


  • DNA
  • Thymidine