Evidence of temporal lobe activation by discriminative spatial orientation

Brain Topogr. 1993 Winter;6(2):137-42. doi: 10.1007/BF01191079.


The results from this spatial orientation, or cue priming, investigation found that targets presented to the contralateral visual fields differentially activated the temporal zones. For instance, stimulation within the right visual field lead to activation of the left temporal zones, as indexed by the relative prominence of the association negativity, N2. The converse was true for left visual field stimulation. For both visual field stimulation, the N2 component also showed an occipital and parietal distribution. The P300 component, which is presumed to be modulated by medial temporal lobe structures, showed the classic centroparietal distribution. Somewhat surprisingly, differences between the primed (e.g., 'facilitated') and 'normal' conditions for the N2 component appeared restricted to the occipital zones. Here, the significant variable was the N2 peak latency. Hence, the priming cue appears to quicken the maximal development of the N2 processing component, preferentially over the occipital cortex, and this may partially explain the faster reaction times in the 'facilitated' conditions for both visual fields.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Brain Mapping
  • Cues
  • Discrimination, Psychological / physiology*
  • Electroencephalography
  • Evoked Potentials, Visual / physiology
  • Female
  • Humans
  • Male
  • Orientation / physiology*
  • Reaction Time / physiology
  • Space Perception / physiology*
  • Temporal Lobe / physiology*
  • Visual Fields / physiology