The Pearson product-moment correlation coefficient is better suited for identification of DNA fingerprint profiles than band matching algorithms

Electrophoresis. 1993 Oct;14(10):967-72. doi: 10.1002/elps.11501401154.

Abstract

A database of DNA fingerprint profiles from permanently established human and animal cell lines was prepared with a computer program originally designed for numerical taxonomy of bacteria. Identifications of cell line DNA profiles were performed, both by the Pearson product-moment correlation coefficient and by band matching. Under the conditions used the Pearson product-moment correlation coefficient was consistently more reliable.

Publication types

  • Comparative Study

MeSH terms

  • Algorithms*
  • Animals
  • Base Sequence
  • Cell Line
  • Chromosome Banding
  • DNA Fingerprinting*
  • Data Interpretation, Statistical*
  • Databases, Factual*
  • Densitometry
  • Humans
  • Molecular Sequence Data
  • Reproducibility of Results