Titanium-containing mesoporous molecular sieves for catalytic oxidation of aromatic compounds

Nature. 1994 Mar 24;368(6469):321-3. doi: 10.1038/368321a0.


Titanium silicalite is an effective molecular-sieve catalyst for the selective oxidation of alkanes, the hydroxylation of phenol and the epoxidation of alkenes in the presence of H2O2 (refs 1-3). The range of organic compounds that can be oxidized is greatly limited, however, by the relatively small pore size (about 0.6 nm) of the host framework. Large-pore (mesoporous) silica-based molecular sieves have been prepared recently by Kresge et al. and Kuroda et al.; the former used a templating approach in which the formation of an inorganic mesoporous structure is assisted by self-organization of surfactants, and the latter involved topochemical rearrangement of a layered silica precursor. Here we describe the use of the templating approach to synthesize mesoporous silica-based molecular sieves partly substituted with titanium--large-pore analogues of titanium silicalite. We find that these materials show selective catalytic activity towards the oxidation of 2,6-di-tert-butyl phenol to the corresponding quinone and the conversion of benzene to phenol.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amines / chemistry
  • Catalysis
  • Crystallography, X-Ray
  • Hydrocarbons / chemistry*
  • Oxidation-Reduction
  • Silicon Dioxide / chemistry*
  • Titanium / chemistry*


  • Amines
  • Hydrocarbons
  • Silicon Dioxide
  • Titanium
  • dodecylamine