Urinary tract infection during pregnancy: its association with maternal morbidity and perinatal outcome

Am J Public Health. 1994 Mar;84(3):405-10. doi: 10.2105/ajph.84.3.405.


Objectives: The effects of antepartum urinary tract infection on adverse maternal and perinatal outcomes were examined. Antepartum urinary tract infection has been previously implicated as a risk factor for numerous outcomes.

Methods: Crude and multivariable analyses were performed with a perinatal registry cohort of 25,746 mother/infant pairs.

Results: Elevated risks were observed for exposure to urinary tract infection and low birthweight, prematurity, preterm low birthweight, premature labor, hypertension/preeclampsia, maternal anemia, and amnionitis. Urinary tract infection was associated with perinatal death only among subjects 20 to 29 years of age.

Conclusions: These findings underscore the importance of antepartum urine screening to identify patients at risk for adverse outcomes.

MeSH terms

  • Adult
  • Cohort Studies
  • Female
  • Humans
  • Infant Mortality
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Infant, Premature
  • Obstetric Labor, Premature / etiology
  • Odds Ratio
  • Pregnancy
  • Pregnancy Complications / etiology
  • Pregnancy Complications, Infectious*
  • Pregnancy Outcome*
  • Retrospective Studies
  • Risk Factors
  • Urinary Tract Infections / complications*