Sexual precocity: sex incidence and aetiology

Arch Dis Child. 1994 Feb;70(2):116-8. doi: 10.1136/adc.70.2.116.

Abstract

The aetiology of 197 girls and 16 boys presenting with sexual precocity was reviewed. Ninety one girls and four boys had central precocious puberty (M:F 23:1); a cause was identified in all the boys but in only six girls. All boys with precocious puberty need detailed investigation; in girls investigation should be based on clinical findings, particularly the consonance of puberty.

MeSH terms

  • Adrenal Hyperplasia, Congenital / complications
  • Androgens / biosynthesis
  • Brain Diseases / complications
  • Breast / growth & development
  • Child
  • Female
  • Gonadotropins / physiology
  • Gonads / physiopathology
  • Humans
  • Hypothalamo-Hypophyseal System / physiopathology
  • Male
  • Puberty, Precocious / etiology*
  • Puberty, Precocious / metabolism
  • Puberty, Precocious / physiopathology
  • Sex Factors

Substances

  • Androgens
  • Gonadotropins