Tc-99m-HMPAO leukocyte scintigraphy for the diagnosis of osteomyelitis in diabetic foot infections

J Foot Ankle Surg. 1993 Nov-Dec;32(6):591-4.


The diagnosis of osteomyelitis in the presence of soft tissue infection and neuropathic bone changes is often difficult in the diabetic foot. Previous attempts at scintigraphic diagnosis included Tc-99m methylene diphosphonate, Gallium-67 citrate and Indium-111 autologous leukocytes (WBCs). A new agent recently available, Technetium-99m-HMPAO labeled white blood cells, shows promise as a scintigraphic agent superior to other agents for this purpose. The authors discuss this agent and present a case report as a preliminary study.

Publication types

  • Case Reports

MeSH terms

  • Diabetes Mellitus, Type 1 / complications
  • Diabetic Foot / complications*
  • Humans
  • Leukocytes*
  • Male
  • Middle Aged
  • Organotechnetium Compounds*
  • Osteomyelitis / complications
  • Osteomyelitis / diagnostic imaging*
  • Oximes*
  • Radionuclide Imaging
  • Technetium Tc 99m Exametazime


  • Organotechnetium Compounds
  • Oximes
  • Technetium Tc 99m Exametazime