Recurrent keratoconus

Cornea. 1994 Jan;13(1):73-7. doi: 10.1097/00003226-199401000-00012.


Keratoconus is a progressive, noninflammatory, nonvascular axial corneal ectasia, with unclear etiology and pathogenesis. It has a prevalence of 50-230 per 100,000 and is a bilateral disorder in up to 90% of cases. The onset of keratoconus is usually at puberty and progresses over 10-20 years producing an irregular myopic astigmatism. The treatment depends on the severity of the irregular astigmatism. Advanced keratoconus, which cannot be treated with contact lenses, requires a surgical procedure--either penetrating keratoplasty, epikeratophakia, or thermokeratoplasty. The results of penetrating keratoplasty are good, with success rates of > 90% of the cases. Recurrence of keratoconus following penetrating keratoplasty has been previously reported, based on a clinical diagnosis, and confirmed by histopathological examination. We report the clinicopathologic features of two further cases of recurrent keratoconus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Contact Lenses
  • Cornea / ultrastructure
  • Graft Rejection / pathology
  • Humans
  • Keratoconus / pathology*
  • Keratoplasty, Penetrating
  • Male
  • Recurrence
  • Reoperation