Myocardial infarction and nicotine patch: a contributing or causative factor?

Eur Heart J. 1993 Dec;14(12):1709-11. doi: 10.1093/eurheartj/14.12.1709.


A case of angina pectoris revealed by nicotine patch treatment is described in a patient who continued to smoke and subsequently suffered a myocardial infarction. The various side effects of nicotine and its derivatives are recalled. The action of nicotine on coronary vasomotricity and its mediators is discussed.

Publication types

  • Case Reports

MeSH terms

  • Administration, Cutaneous
  • Adult
  • Humans
  • Male
  • Myocardial Infarction / chemically induced
  • Myocardial Infarction / etiology*
  • Nicotine / administration & dosage
  • Nicotine / adverse effects*
  • Smoking / adverse effects
  • Smoking / drug therapy
  • Smoking Cessation / methods


  • Nicotine