Germ cell tumors of the ovary arising after dermoid cyst resection: a long-term follow-up study

Obstet Gynecol. 1994 Apr;83(4):605-8. doi: 10.1097/00006250-199404000-00021.


Objective: To study the long-term ovarian neoplastic consequences of resection of a dermoid cyst.

Methods: The study population comprised 99 patients who were operated on for an ovarian dermoid cyst. Follow-up information was obtained for 91 women for a mean period of 5.06 +/- 2.46 years.

Results: Of the 99 women, 18 had bilateral dermoid cysts. Multiple dermoid cysts in a single ovary were found in nine of the women with bilateral cysts and in one of the remaining patients. Two patients developed malignant germ cell tumors, and three developed a recurrent dermoid cyst in an ovary from which a dermoid cyst had previously been extracted. Bilateral or multiple ovarian dermoid cysts were present at the initial operation in four (80%) of these patients.

Conclusions: Women with bilateral or multiple dermoid cysts may include a subgroup of patients with a greater tendency to develop future ovarian germ cell neoplasms.

Publication types

  • Review

MeSH terms

  • Adult
  • Dermoid Cyst / pathology
  • Dermoid Cyst / surgery*
  • Female
  • Follow-Up Studies
  • Germinoma / epidemiology*
  • Humans
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Neoplasms, Second Primary / epidemiology*
  • Ovarian Neoplasms / epidemiology*
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / surgery*
  • Time Factors