Cerebro-reno-digital syndrome in two sibs

Am J Med Genet. 1993 Sep 1;47(3):420-2. doi: 10.1002/ajmg.1320470325.

Abstract

We describe two sibs with mental retardation, facial anomalies, polydactyly, cerebellar vermis agenesis, and either meningocele or renal cystic dysplasia. The patients' condition appears to belong to a group of cerebro-reno-digital syndromes. Autosomal recessive inheritance is suggested.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abnormalities, Multiple / genetics*
  • Cerebellum / abnormalities*
  • Face / abnormalities
  • Female
  • Genes, Recessive
  • Humans
  • Infant, Newborn
  • Intellectual Disability / genetics*
  • Kidney Diseases, Cystic / genetics*
  • Male
  • Meningocele / genetics
  • Pedigree
  • Polydactyly / genetics*
  • Seizures / genetics
  • Syndrome