Fluorescence in situ hybridization in cancer and radiation biology

Radiat Res. 1994 Mar;137(3):275-89.


This review describes molecular cytogenetic approaches to genetic analysis including fluorescence in situ hybridization, primed in situ labeling and comparative genomic hybridization. It also summarizes the applications of this technology to physical mapping, cancer diagnosis and prognostication and in radiation biology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Chromosome Mapping
  • DNA Probes
  • Humans
  • In Situ Hybridization, Fluorescence*
  • Microscopy / methods
  • Neoplasms / diagnosis*
  • Neoplasms / genetics
  • Radiobiology / methods*


  • DNA Probes