Variation among rheumatologists in the use of prednisone and second-line agents for the treatment of rheumatoid arthritis

Arthritis Rheum. 1994 Apr;37(4):476-80. doi: 10.1002/art.1780370407.

Abstract

Objective: To test for and estimate variation among rheumatologists in their prescribing of prednisone and second-line agents for the treatment of rheumatoid arthritis (RA), after taking into account the characteristics of their patients.

Methods: Multiple logistic regression incorporating random effects for rheumatologists, with adjustment for patient characteristics.

Results: Values for the likelihood-ratio statistic provided strong evidence of such variation. Random-effect variance estimates showed that the variation is of great magnitude.

Conclusion: Even after patient characteristics have been taken into account, the data show that the rheumatologist may strongly influence the use of prednisone and second-line agents by a patient.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analysis of Variance
  • Anti-Inflammatory Agents / therapeutic use
  • Arthritis, Rheumatoid / drug therapy*
  • Drug Prescriptions / statistics & numerical data*
  • Drug Therapy, Combination
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Prednisone / therapeutic use*
  • Random Allocation
  • Severity of Illness Index
  • Socioeconomic Factors

Substances

  • Anti-Inflammatory Agents
  • Prednisone