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Comparative Study
. Winter 1994;6(1):23-9.
doi: 10.1176/jnp.6.1.23.

A Survey of the Phenomenology and Pharmacotherapy of Compulsive and Impulsive-Aggressive Symptoms in Prader-Willi Syndrome

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Comparative Study

A Survey of the Phenomenology and Pharmacotherapy of Compulsive and Impulsive-Aggressive Symptoms in Prader-Willi Syndrome

D J Stein et al. J Neuropsychiatry Clin Neurosci. .

Abstract

Prader-Willi Syndrome (PWS) is a congenital disorder characterized by hyperphagia as well as by other behavioral disturbances such as self-mutilation and temper outbursts. Some of these symptoms have been reported to respond to psychotropic medications. A systematic survey was conducted to gather information on the phenomenology and pharmacotherapy of compulsive and impulsive-aggressive symptoms in PWS. Both compulsive and impulsive-aggressive symptoms are frequent in this population. Pharmacotherapeutic intervention may have a role in the management of these symptoms. Rigorous diagnostic and treatment studies should be undertaken in this population.

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