A survey of the phenomenology and pharmacotherapy of compulsive and impulsive-aggressive symptoms in Prader-Willi syndrome

J Neuropsychiatry Clin Neurosci. Winter 1994;6(1):23-9. doi: 10.1176/jnp.6.1.23.

Abstract

Prader-Willi Syndrome (PWS) is a congenital disorder characterized by hyperphagia as well as by other behavioral disturbances such as self-mutilation and temper outbursts. Some of these symptoms have been reported to respond to psychotropic medications. A systematic survey was conducted to gather information on the phenomenology and pharmacotherapy of compulsive and impulsive-aggressive symptoms in PWS. Both compulsive and impulsive-aggressive symptoms are frequent in this population. Pharmacotherapeutic intervention may have a role in the management of these symptoms. Rigorous diagnostic and treatment studies should be undertaken in this population.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Deglutition Disorders / etiology
  • Drug Therapy*
  • Humans
  • Mental Disorders / etiology
  • Prader-Willi Syndrome / diagnosis*
  • Prader-Willi Syndrome / drug therapy*
  • Prader-Willi Syndrome / psychology
  • Self Mutilation / etiology
  • Surveys and Questionnaires