Langerhans' cell histiocytosis associated with Hodgkin's disease: a case report

J Natl Med Assoc. 1994 Jan;86(1):65-9.


A patient who developed pulmonary Langerhans' cell histiocytosis after chemotherapy for nodular sclerosing Hodgkin's disease is presented. Twenty-one cases of Langerhans' cell histiocytosis associated with Hodgkin's disease have been reported in the literature. Such an association seems to be more than fortuitous. The possibilities of a common etiological agent inducing both Hodgkin's disease and Langerhans' cell histiocytosis and of a reactive proliferation of Langerhans' cells after radiotherapy or chemotherapy for Hodgkin's disease are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Histiocytosis, Langerhans-Cell / complications*
  • Histiocytosis, Langerhans-Cell / drug therapy
  • Hodgkin Disease / complications*
  • Hodgkin Disease / drug therapy
  • Humans
  • Pregnancy
  • Pregnancy Complications, Hematologic* / drug therapy
  • Pregnancy Complications, Neoplastic* / drug therapy