Human visceral leishmaniasis in Alpes-Maritimes, France: epidemiological characteristics for the period 1985-1992

Trans R Soc Trop Med Hyg. Jan-Feb 1994;88(1):33-4. doi: 10.1016/0035-9203(94)90485-5.

Abstract

In 8 years (1985-1992), 65 cases of human visceral leishmaniasis (HVL) have been diagnosed in the department of Alpes-Maritimes, France, 56 of them having been infected locally. The annual frequency has increased from 3 cases in 1985 to 15 cases in 1992. There is a low rate of paediatric cases (29%) and a predominance of males among adult cases (85%). Since 1986, 19 cases of co-infection with Leishmania and human immunodeficiency virus 1 have been reported, corresponding to 40% of adult cases and to 30% of the total cases. The frequency of co-infections is stable at about 3 per annum. Isoenzymatic identification of the strains isolated from patients confirmed Leishmania infantum zymodeme MON-1 as responsible for most if not all HVL in the department of Alpes-Maritimes; 42 of the 44 strains isolated belonged to that zymodeme.

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Child
  • Child, Preschool
  • Female
  • France / epidemiology
  • HIV Infections / complications
  • HIV-1
  • Humans
  • Incidence
  • Infant
  • Leishmania infantum* / classification
  • Leishmaniasis, Visceral / complications
  • Leishmaniasis, Visceral / epidemiology*
  • Leishmaniasis, Visceral / parasitology
  • Male