Helicobacter pylori: microbiology of a 'slow' bacterial infection

Trends Microbiol. 1993 Oct;1(7):255-60. doi: 10.1016/0966-842x(93)90047-u.


The bacterium Helicobacter pylori lives in the gastric mucus layer of humans and induces a chronic inflammatory response that can result in both peptic ulceration and gastric neoplasms. Helicobacter pylori infection can be considered as a 'slow', adaptive and autoregulating process. The mechanisms by which this slow bacterial pathogen survives and interacts with the host immune system may provide a model for other persistent mucosal pathogens.

Publication types

  • Review

MeSH terms

  • Gastritis / etiology
  • Helicobacter Infections / etiology*
  • Helicobacter pylori / pathogenicity*
  • Humans