An outbreak of group B streptococcus infection in a neonatal nursery and subsequent trial for prophylaxis of nosocomial transmission

Acta Paediatr Jpn. 1994 Feb;36(1):88-90. doi: 10.1111/j.1442-200x.1994.tb03137.x.


An outbreak of sepsis and meningitis caused by group B streptococcus occurred in three very low birthweight infants. To prevent further nosocomial transmission, immune globulin and ampicillin sodium were administered intravenously to other very low birthweight infants. After this prophylaxis, no other infants were involved in this outbreak. Immuno- and chemoprophylaxis may be considered as procedures to prevent nosocomial infection for very low birthweight infants.

Publication types

  • Case Reports

MeSH terms

  • Ampicillin / therapeutic use
  • Cross Infection / prevention & control*
  • Disease Outbreaks*
  • Female
  • Humans
  • Immunoglobulins, Intravenous
  • Infant
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Injections, Intravenous
  • Meningitis / microbiology
  • Nurseries, Hospital*
  • Streptococcal Infections / epidemiology*
  • Streptococcus agalactiae*


  • Immunoglobulins, Intravenous
  • Ampicillin