The yeast actin cytoskeleton

Curr Opin Cell Biol. 1994 Feb;6(1):110-9. doi: 10.1016/0955-0674(94)90124-4.


Budding and fission yeast present significant advantages for studies of the actin cytoskeleton. The application of classical and molecular genetic techniques provides a facile route for the analysis of structure/function relationships, for the isolation of novel proteins involved in cytoskeletal function, and for deciphering the signals that regulate actin assembly in vivo. This review focuses on the budding yeast Saccharomyces cerevisiae and also identifies some recent advances from studies on the fission yeast Schizosaccharomyces pombe, for which studies on the actin cytoskeleton are still in their infancy.

Publication types

  • Review

MeSH terms

  • Actins / chemistry
  • Actins / genetics
  • Actins / physiology*
  • Cell Cycle
  • Cytoskeleton / physiology*
  • Cytoskeleton / ultrastructure
  • Genes, Fungal
  • Microfilament Proteins / genetics
  • Microfilament Proteins / metabolism
  • Microfilament Proteins / physiology
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / physiology*
  • Saccharomyces cerevisiae / ultrastructure
  • Schizosaccharomyces / genetics
  • Schizosaccharomyces / physiology*
  • Signal Transduction


  • Actins
  • Microfilament Proteins