Direct screening of a mitochondrial DNA deletion valuable for Amerindian evolutionary research

Hum Genet. 1994 Apr;93(4):435-6. doi: 10.1007/BF00201670.


A rapid, simple restriction isotyping method is described for the direct screening of a previously characterized Amerindian mitochondrial DNA (mtDNA) marker consisting of a 6-bp "Huetar" deletion. In a sample of 31 maternally non-related Chibchan Amerindian Bribri from Costa Rica, this deletion was present in 74%, arguing for the usefulness of this private polymorphism for Amerindian taxonomic research.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Biological Evolution
  • DNA, Mitochondrial / genetics*
  • Humans
  • Indians, Central American / genetics*
  • Molecular Sequence Data
  • Sequence Deletion*


  • DNA, Mitochondrial