Appraisal of skin tests with food extracts for diagnosis of food hypersensitivity

Clin Allergy. 1978 Nov;8(6):559-64. doi: 10.1111/j.1365-2222.1978.tb01509.x.


Seventy-six children aged 5 months to 15 years who exhibited a net weal of 3.0 mm or greater to a puncture skin test with one or more of fourteen foods were subjected to double-blind food challenge. Confirmed reactions to double-blind food challenge were found to occur only with peanut, milk, egg and soybean. Puncture skin tests with 1:20 w/v concentration of food extracts identified all subjects who exhibited an adverse reaction during the double-blind food challenge. Performance of intradermal skin tests did not identify any additional subjects who reacted clinically to double-blind food challenge.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Clinical Trials as Topic
  • Food Hypersensitivity / diagnosis*
  • Food*
  • Histamine Release
  • Humans
  • Infant
  • Intradermal Tests
  • Leukocytes
  • Skin Tests