CC chemokines in allergic inflammation

Immunol Today. 1994 Mar;15(3):127-33. doi: 10.1016/0167-5699(94)90156-2.


CC chemokines are small inducible proteins that are related to interleukin 8. Recent studies have shown that several CC chemokines, MCP-1, MCP-3, RANTES and MIP-1 alpha, act on basophils and/or eosinophils via GTP-binding protein-coupled receptors. Marco Baggiolini and Clemens Dahinden discuss the involvement of CC chemokines in the recruitment and activation of the main effector cells of allergic inflammation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Basophils / physiology
  • Chemotactic Factors / physiology*
  • Cytokines / physiology*
  • Eosinophils / physiology
  • Humans
  • Hypersensitivity / immunology
  • Inflammation / immunology*
  • Molecular Sequence Data


  • Chemotactic Factors
  • Cytokines