Cytoskeletal events in growth cone steering

Curr Opin Neurobiol. 1994 Feb;4(1):43-8. doi: 10.1016/0959-4388(94)90030-2.


Oriented neural outgrowth is dependent upon the capability of growth cones to reorient the direction of their migration in response to contact with guidance information. Recent observations have directed attention toward the role of actin distribution and concentration in transmitting localized peripheral signals to central elements of the growth cone, particularly microtubules.

Publication types

  • Review

MeSH terms

  • Actins / metabolism
  • Actins / physiology
  • Animals
  • Cytoskeleton / physiology*
  • Microtubules / physiology
  • Neurons / physiology*


  • Actins