Chondroitin sulfate proteoglycan-immunoreactivity of lectin-labeled perineuronal nets around parvalbumin-containing neurons

Brain Res. 1994 Jan 28;635(1-2):307-11. doi: 10.1016/0006-8993(94)91452-4.


Perineuronal nets represent highly specialized glial and glia-associated structures. In this study, a triple fluorescence labeling of chondroitin sulfate proteoglycan-immunoreactive (CSPG-ir) and N-acetylgalactosamine (GalNac)-specific plant lectin Wisteria floribunda agglutinin (WFA) binding net components as well as parvalbumin-immunoreactivity (-ir) was performed. It was shown in the rat cortex, that the same nets frequently surrounding parvalbumin-ir neurons are stained by CSPG-ir as well as by the lectin binding method.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chondroitin Sulfate Proteoglycans / analysis*
  • Fluorescent Antibody Technique
  • Immunoenzyme Techniques
  • Lectins
  • Nerve Net / chemistry*
  • Neurons / chemistry*
  • Parvalbumins / analysis*
  • Plant Lectins*
  • Rats
  • Rats, Wistar
  • Receptors, N-Acetylglucosamine


  • Chondroitin Sulfate Proteoglycans
  • Lectins
  • Parvalbumins
  • Plant Lectins
  • Receptors, N-Acetylglucosamine
  • wisteria lectin