Prolonged treatment with almitrine for refractory hypoxemia in adult respiratory distress syndrome

Chest. 1994 May;105(5):1579-80. doi: 10.1378/chest.105.5.1579.

Abstract

A 49-year-old man presented with an atypical pneumonia entailing an adult respiratory distress syndrome (ARDS). The refractory hypoxemia caused a myocardial infarction, leading us to try pharmacologic treatments. Almitrine bismesilate (AB) infusion allowed improvement of arterial oxygenation during 115 h without adverse effect. This case is, to our knowledge, the first reported prolonged treatment using AB for hypoxemia due to ARDS.

Publication types

  • Case Reports

MeSH terms

  • Almitrine / administration & dosage*
  • Hemodynamics / drug effects
  • Humans
  • Hypoxia / drug therapy*
  • Hypoxia / etiology
  • Infusions, Intravenous
  • Male
  • Middle Aged
  • Pulmonary Gas Exchange / drug effects
  • Respiratory Distress Syndrome / complications
  • Respiratory Distress Syndrome / drug therapy*
  • Respiratory Distress Syndrome / physiopathology

Substances

  • Almitrine