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Clinical Trial
. 1993 Feb;57(2):170-4.
doi: 10.1093/ajcn/57.2.170.

Vitamin C Supplementation Reduces the Incidence of Postrace Symptoms of Upper-Respiratory-Tract Infection in Ultramarathon Runners

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Clinical Trial

Vitamin C Supplementation Reduces the Incidence of Postrace Symptoms of Upper-Respiratory-Tract Infection in Ultramarathon Runners

E M Peters et al. Am J Clin Nutr. .

Abstract

This study determined whether daily supplementation with 600 mg vitamin C would reduce the incidence of symptoms of upper-respiratory-tract (URT) infections after participation in a competitive ultramarathon race (> 42 km). Ultramarathon runners with age-matched controls were randomly divided into placebo and experimental (vitamin C-supplemented) groups. Symptoms of URT infections were monitored for 14 d after the race. Sixty-eight percent of the runners in the placebo group reported the development of symptoms of URT infection after the race; this was significantly more (P < 0.01) than that reported by the vitamin C-supplemented group (33%). The duration and severity of symptoms of URT infections reported in the vitamin C-supplemented nonrunning control group was also significantly less than in the nonrunning control group receiving the placebo (P < 0.05). This study provides evidence that vitamin C supplementation may enhance resistance to the postrace URT infections that occur commonly in competitive ultramarathon runners and may reduce the severity of such infections in those who are sedentary.

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