Irreversible cardiomyopathy due to thyrotoxicosis

Cardiology. 1994;84(4-5):274-7. doi: 10.1159/000176411.


We report 4 adult patients with thyrotoxicosis accompanied by irreversible low-output heart failure. Each patient showed elevated plasma levels of thyroid hormone and prolonged low-output heart failure even after thyroid function returned to normal. Specimens of the right ventricular myocardium stained with anti-beta myosin heavy-chain MAb showed a normal staining pattern with a predominance of the beta-form. Our observations suggest that thyrotoxicosis may be one possible cause of irreversible cardiomyopathy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cardiac Output, Low / etiology*
  • Cardiac Output, Low / pathology
  • Cardiomyopathies / etiology
  • Cardiomyopathies / pathology
  • Heart Ventricles / pathology
  • Humans
  • Male
  • Middle Aged
  • Thyrotoxicosis / complications*