A case of Hutchinson-Gilford progeria syndrome mimicking scleredema in early infancy

Dermatology. 1994;188(4):318-21. doi: 10.1159/000247175.


We report a case of Hutchinson-Gilford progeria syndrome (HGPS). The patient showed the characteristics of scleredema at the age of 2.5 months but developed all the manifestations of HGPS gradually until 10 months old. The possibility of development of HGPS should by considered in any case of scleredema at birth or in early infancy.

Publication types

  • Case Reports

MeSH terms

  • Alopecia / pathology
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Infant, Newborn
  • Progeria / diagnosis*
  • Progeria / pathology
  • Sclerema Neonatorum / diagnosis*
  • Sclerema Neonatorum / pathology