Screening and treatment of asymptomatic bacteriuria in pregnancy prevent pyelonephritis

J Infect Dis. 1994 Jun;169(6):1390-2. doi: 10.1093/infdis/169.6.1390.


Although asymptomatic bacteriuria during pregnancy is associated with an increased risk of developing pyelonephritis, the effectiveness of screening programs to reduce this risk is controversial. A sharp reduction in the annual incidence of pyelonephritis (1.8% to 0.6%, P < .001) occurred after the introduction of a program to screen and treat asymptomatic bacteriuria among pregnant women followed at a large teaching hospital. The data provide retrospective and prospective evidence that screening and treatment programs for asymptomatic bacteriuria during pregnancy reduce the risk of pyelonephritis in a population with a moderate to high prevalence of bacteriuria.

MeSH terms

  • Bacteria / isolation & purification
  • Bacteriuria / complications
  • Bacteriuria / diagnosis*
  • Bacteriuria / epidemiology
  • Female
  • Humans
  • Incidence
  • Mass Screening
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis*
  • Prevalence
  • Pyelonephritis / epidemiology
  • Pyelonephritis / microbiology
  • Pyelonephritis / prevention & control*
  • Urinalysis