An evaluation of vesical urodynamics before renal transplantation and its effect on renal allograft function and survival

Transplantation. 1994 May 27;57(10):1455-7.


This prospective study investigated the urodynamics of the urinary bladder prior to renal transplantation in 57 patients and related this to graft function and transplantation outcome. The study demonstrated a clear deterioration in the pretransplant urodynamic characteristics in all subgroups, with male patients in the hemodialysis group (HD) showing a more substantial decline: 1st sensation volume (ml) in male HD patients = 112 (120) vs. 171 (173) in male CAPD patients, P < 0.05; and corresponding average flow rate for same groups 3 (3) ml/sec vs. 5 (5) ml/sec, P < 0.05. Figures are median (interquartile range). We have identified a subgroup of patients with a small bladder capacity (less than 100 ml) who have a reduced graft survival (55% vs. 92% for bladders larger than 100 ml at 2 years) apparently unrelated to immunological processes.

MeSH terms

  • Adult
  • Female
  • Graft Survival
  • Humans
  • Kidney / physiology
  • Kidney Transplantation*
  • Male
  • Middle Aged
  • Prospective Studies
  • Surveys and Questionnaires
  • Urinary Bladder / physiology*
  • Urinary Tract Infections / complications