Prevalence of impaired growth in children with homozygous sickle cell anemia

Am J Med Sci. 1994 Jun;307(6):405-7. doi: 10.1097/00000441-199406000-00004.


The prevalence of impaired growth was evaluated in 63 patients with homozygous sickle cell anemia. Twenty-five percent of the children studied were less than the fifth percentile of National Center for Health Statistics growth standards for either height/age, weight/age, or weight/height. Significantly more 11- to 18-year-old children were less than the fifth percentile for weight/height compared with earlier age ranges. No differences due to gender were found. Nutritional intervention may improve growth in selected children.

MeSH terms

  • Adolescent
  • Anemia, Sickle Cell / complications*
  • Anemia, Sickle Cell / genetics
  • Child
  • Child, Preschool
  • Female
  • Growth Disorders / complications*
  • Homozygote
  • Humans
  • Male