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Comparative Study
, 135 (1-2), 159-64

A Field Isolate of Sendai Virus: Its High Virulence to Mice and Genetic Divergence Form Prototype Strains

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Comparative Study

A Field Isolate of Sendai Virus: Its High Virulence to Mice and Genetic Divergence Form Prototype Strains

T Sakaguchi et al. Arch Virol.

Abstract

A field isolate of Sendai virus, the Hamamatsu strain, was far more virulent in mice than the prototype Z strain. The Hamamatsu strain replicated more efficiently in the mouse lung than the Z strain, causing deteriorating lung lesions. Nucleotide sequence analysis of the HN, F and M genes revealed that the Hamamatsu strain was divergent from the prototype Z, Harris and Fushimi strains.

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